Life Inverted

L I F E  I N V E R T E D

A documentary about mast cell activation syndrome  


Toxicant Induced Loss of Tolerance and Mast Cell Activation Syndrome is currently affecting 1 in 6 people around the world. It is a relentless condition that does not discriminate.

The very nature of these afflictions turns a person’s world upside down. They are disorientated and their life always starts at the other end of the spectrum. Completely upside down from society.

The awareness this documentary will bring is crucial for the patients and the medical community, who need to be prepared to properly treat them.

Life Inverted will focus on the narrative of a patient and doctor discovering the condition for the first time, and the journey that takes them on, in a visually engaging documentary.


The ambition of this documentary has seen its production span the Atlantic, with shoots in Seattle, Minneapolis, New York, and London. These interviews were with some of the leading professionals in their field and included shoots at Harvard.

Life Inverted has just wrapped in Seattle and is now with our Editor in Madrid.


The film will be released this spring.

Director: James Hughes
Format: Feature
Genre: Documentary
Shot on: Arri Alexa Mini
Ratio: 2.40:1
Length: 100 Minutes